Health & biology · 2025

Twice-yearly HIV prevention

A lenacapavir injection every six months prevented nearly all HIV infections in trials.

In the PURPOSE 1 trial there were zero infections among over 2,000 women receiving it. The FDA approved it for prevention as Yeztugo in June 2025.

Arcs above join it to what it stood on, arcs below to what it led to. The bar places this stretch on the tree's whole timeline.

What it built on 1

The dashed line marks when it first worked.

Life expectancy at birth Latest: 73.2 years (2023) Source: Our World in Data