Health & biology · 2023

Casgevy, first CRISPR therapy

The first approved CRISPR medicine freed sickle cell patients from painful crises.

Vertex and CRISPR Therapeutics' Casgevy edits patients' blood stem cells to restore fetal haemoglobin. The UK approved it in November 2023 and the US in December 2023.

See it in the living tree Wikipedia

Arcs above join it to what it stood on, arcs below to what it led to. The bar places this stretch on the tree's whole timeline.

What it built on 1

CRISPR gene editing 2012

What it led to 1

Routine in-body gene editing ~2032

Related measurements

The dashed line marks when it first worked.

Cost to sequence a human genome Latest: 525 $ (2022) Source: Our World in Data