Health & biology · 2024

AlphaFold 3

Extended structure prediction to protein complexes with DNA, RNA and drug molecules.

Published by Google DeepMind and Isomorphic Labs in May 2024, AlphaFold 3 uses a diffusion model to predict how biomolecules bind. It targets drug design, where interactions matter more than single folds.

See it in the living tree Wikipedia

Arcs above join it to what it stood on, arcs below to what it led to. The bar places this stretch on the tree's whole timeline.

What it built on 2

AlphaFold 2 2020
Denoising diffusion (DDPM) 2020

What it led to 2

AlphaGenome 2026
Therapies that slow ageing ~2040

Watch

AlphaFold Server Demo - Google DeepMindGoogle DeepMind · YouTube

Related measurements

The dashed line marks when it first worked.

Training compute of notable AI models Source: Epoch AI, Notable AI Models (CC BY 4.0)

Best AI score on GPQA Diamond Latest: 95.8 % correct (2026) Source: Epoch AI, Capabilities & benchmarking (benchmark_data.zip, gpqa_diamond.csv); Anthropic: Claude 3 public launch (March 4, 2024)