Health & biology · December 2025

GLP-1 pill for obesity

Obesity treatment moves from injection to a daily pill.

The FDA approved oral semaglutide 25 mg for weight loss. In the 64-week OASIS 4 trial, patients on treatment lost about 17% of body weight versus 3% on placebo.

See it in the living tree Wikipedia Source

Arcs above join it to what it stood on, arcs below to what it led to. The bar places this stretch on the tree's whole timeline.

What it built on 1

Semaglutide 2017

What it led to 1

Orforglipron 2026

Related measurements

The dashed line marks when it first worked.

Life expectancy at birth Latest: 73.2 years (2023) Source: Our World in Data